Inhibition of platelet aggregation by protease inhibitors. Possible involvement of proteases in platelet aggregation

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Inhibition of platelet aggregation by protease inhibitors. Possible involvement of proteases in platelet aggregation.

The possible participation of proteases in human platelet aggregation was explored using various protease inhibitors and substrates. Protease inhibitors used included naturally occurring inhibitors of serine proteases and synthetic inhibitors that modify the active site of protease. Substrates used were synthetic substrates for the trypsin type as well as for the chymotrypsin type of protease. ...

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ژورنال

عنوان ژورنال: Blood

سال: 1978

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v52.1.1.1